Webinars and Talks on the Latest Advancements on nTMS

Nexstim Podium

Nexstim Webinars

We are bringing renowned speakers to you free of charge, pulling together some of the most exciting talks from the past few months and offering researchers and clinicians a virtual podium to showcase their most recent work live.

Webinars and Talks On-Demand

Have a look at our video offerings by topic:

 

If you would like us to notify you on topics of interest to you, please fill out the form at the bottom of this page. 

 

Interested in a live demo of nTMS?

Our team of physicians, researchers, and engineers is prepared to answer your questions. If you would like to learn more or set up a virtual demonstration for your team, please contact us at info@nexstim.com

Pain

Hear from experienced clinicians and researchers, how they utilize rTMS to alleviate chronic neuropathic pain in their patients. 

  • Learn which stimulation parameters and protocols they use
  • See which patients benefit the most from navigated rTMS therapy
  • Find out how rTMS can be used in patients suffering from both chronic neuropathic pain and depression

Please note that Nexstim nTMS Systems are CE-marked, but do not have FDA clearance for the treatment of chronic neuropathic pain, for investigational use in the US only.

Post-operative paresis

Hear from experienced clinicians and researchers, how they utilize navigated low-frequency rTMS to aid in the recovery of patients suffering from post-surgical paresis.

  • Learn which stimulation parameters and protocols they use
  • Find out how they combined rTMS with physical therapy for optimal results
  • See real case examples of patients benefiting from rTMS treatment after post-surgical paresis

Please note that Nexstim nTMS Systems do not have an FDA clearance nor a CE mark for postoperative paresis treatment. Researchers are utilizing the Nexstim NBS System for post-operative paresis as a research utility only.

Pre-operative mapping

See examples from various centers on how nTMS motor and language mapping data results can be used pre- and intraoperatively for neurosurgery and radiotherapy planning. 

TMS Basics & Pediatrics

Clinicians from leading pediatric centers are showing how nTMS can be used in the pediatric population.

TMS-EEG

Researchers are showing how to connect neuronavigated TMS with EEG, to maximize the impact of TMS on the cortex while minimizing the contribution of artifacts and confounding factors, to collect reliable brain responses. 

Learn more about TMS-EEG from our dedicated TMS-EEG research page.

Please note that Nexstim nTMS Systems do not have an FDA clearance nor a CE mark for TMS-EEG use. Researchers are utilizing the Nexstim NBS System for TMS-EEG as a research utility only.

Spinal Cord Injury

Dr. Anastasia Shulga, MD, talks about the combination of PAS (paired associative stimulation) with high-frequency PNS (peripheral nerve stimulation) and E-field guided high-intensity TMS as a potential therapy for spinal cord injury patients:

  • See before and after videos of patients suffering from spinal cord injury, showing restoration of upper and lower limb motor function after PAS
  • Learn which parameters the team at Helsinki University Hospital utilizes to achieve promising results
  • Hear about a currently ongoing, sham-controlled, double-blind, randomized clinical trial

Please note that Nexstim nTMS Systems do not have an FDA clearance nor a CE mark for spinal cord injury rehabilitation. Helsinki University Hospital is utilizing the Nexstim NBS System for chronic spinal cord injury therapy as a research utility only.

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Nexstim NBS 5 for Pre-Surgical Mapping: Indications for use

The Nexstim Navigated Brain Stimulation (NBS) System 5 is indicated for non-invasive mapping of the primary motor cortex of the brain to its cortical gyrus. The Nexstim NBS System 5 provides information that may be used in the assessment of the primary motor cortex for pre-procedural planning.

Nexstim NexSpeech®, when used together with the NBS System 5, is indicated for non-invasive localization of cortical areas that do not contain essential speech function. NexSpeech® provides information that may be used in pre-surgical planning in patients undergoing brain surgery. Intra-operatively, the localization information provided by NexSpeech® is intended to be verified by direct cortical stimulation.

The Nexstim NBS System 5 and NBS System 5 with NexSpeech® are not intended to be used during a surgical procedure.

The Nexstim NBS System 5 and NBS System 5 with NexSpeech® are intended to be used by trained clinical professionals.

 

Nexstim NBS 6 for Depression Therapy: Indications for use

INDICATIONS FOR USE

CE mark and FDA clearance (K170902, K182700): Nexstim NBS 6 is indicated for the treatment of Major Depressive Disorder in adult patients who have failed to achieve satisfactory improvement from prior antidepressant medication in the current episode.

NBS 6 THERAPY SHOULD NOT BE GIVEN TO

  1. Patients with non-removable conductive, ferromagnetic, or other magnetic-sensitive metal anywhere in the head or within 30 cm (12 in) of the stimulation coil. Examples include cochlear implants, implanted electrodes or stimulators, aneurysm clips or coils, stents, bullet fragments, ocular implants, and stents.
  2. Patients who have an active or inactive implanted device (including device leads), including deep brain stimulators, cochlear implants, cardiac pacemakers, and vagus nerve stimulators. Contraindicated use could result in serious injury or death.
  3. Patients with increased intracranial pressure or patients with intracardiac lines, intravenous pumps, or dose calculators. 

Failure to follow these restrictions could result in serious injury or death.

RISKS AND SIDE EFFECTS

Seizures (convulsions): Cortical magnetic stimulation runs the risk of inducing seizures; although they are rare. Under ordinary clinical use, the estimated risk of seizure is approximately 1 in 30 000 treatments (0.003%) or 1 in 1000 patients (0.1%). 

Headache: The most common side effects reported during clinical trials are mild headache (~50% of TMS treatment group) and scalp pain or discomfort (35.8%). In general, headache and pain on the stimulation site have been generally mild to moderate and occurring less frequently after the first week of treatment. The reason for headache may be the tension of scalp and neck muscles due to an uncomfortable and stressful situation.

Muscle Twitching:  You may feel twitches in the muscles of your arm, leg or face during the magnetic stimulation. This is a common sensation but not hazardous. The twitches will stop when the magnetic stimulation stops.

Skin Irritation:  There is a small risk of mild skin irritation at the location where the muscle electrode sensors have been placed, but this usually consists of minor redness that will go away quickly after they are removed.

Changes in hearing:  The loud “click” produced by the TMS stimulator can cause temporary hearing changes following treatment.  This is prevented by wearing soft foam ear plugs during treatment. No problems with hearing due to TMS have ever occurred when earplugs have been properly worn

INEFFECTIVE TREATMENT

There is no evidence that single therapy sessions would improve mood.  rTMS treatment effects in reducing depression are temporary, and patients may need to continue other forms of depression therapy. Relapse into depression is likely without follow-up treatment. Notify your doctor in case of worsening depression or suicidality. 

CAUTION: SPECIAL POPULATIONS

All patients must be screened for the characteristics listed in this section and excluded without clear benefit or compelling clinical reason.
The safety and effectiveness of Nexstim TMS treatment has not been established in the following patient populations:

  • Younger than 22 years or older than 70 years
  • Suicide plan or recent suicide attempt
  • History of concurrent use of electroconvulsive therapy (ECT) or vagus nerve stimulation (VNS)
  • Depression secondary to a general medical condition or substance-induced
  • Seasonal affective disorder
  • History of substance abuse, obsessive compulsive disorder, or post-traumatic stress disorder
  • A psychotic disorder, including schizoaffective disorder, bipolar disorder, or major depression with psychotic features
  • History of increased intracranial pressure or head trauma
  • Cardiac pacemakers, implantable cardioverter defibrillators, ocular implants, deep brain stimulators, vagus nerve stimulators, implanted medication pumps, intracardiac lines, or significant cardiac disease
  • Pregnant or nursing

Nexstim NBS 6 for Chronic Pain Therapy: Indications for use (CE mark) and patient safety

Nexstim NBS 6 is not approved by the Food and Drug Administration for commercial use of the treatment of chronic pain in the United States, for investigational use only.

CE mark Intended use

Nexstim NBS 6 for depression is intended to be used for treatment of major depressive disorder (MDD) by targeting and delivering non-invasive repetitive TMS stimulation to the patient's dorsolateral prefrontal cortex.

CE mark Indications for use

Nexstim NBS 6 is indicated for MRI-guided and electric field (or E-field) navigated, non-invasive, repetitive TMS stimulation (rTMS) of the motor cortex as therapy to alleviate chronic unilateral neuropathic pain in adult patients. Nexstim NBS 6 is intended to be used by trained clinical professionals. 

SAFETY

NBS 6 THERAPY SHOULD NOT BE GIVEN TO

  1. Patients with non-removable conductive, ferromagnetic, or other magnetic-sensitive metal anywhere in the head or within 30 cm (12 in) of the stimulation coil. Examples include cochlear implants, implanted electrodes or stimulators, aneurysm clips or coils, stents, bullet fragments, ocular implants, and stents.
  2. Patients who have an active or inactive implanted device (including device leads), including deep brain stimulators, cochlear implants, cardiac pacemakers, and vagus nerve stimulators. Contraindicated use could result in serious injury or death.
  3. Patients with increased intracranial pressure or patients with intracardiac lines, intravenous pumps, or dose calculators. 

Failure to follow these restrictions could result in serious injury or death.

RISKS AND SIDE EFFECTS

Seizures (Convulsions): Cortical magnetic stimulation runs the risk of inducing seizures;  although they are rare.

The most common side effects reported during clinical studies (Lefaucheur et al., Nurmikko et al.) are: mild headache (25% of the TMS treatment group), sleepiness (38 %), and dizziness (15 %).

No severe adverse events were reported. Specifically, no seizures occurred.

In some patients with chronic neuropathic pain, the pain may transiently worsen after rTMS stimulation. The increase in pain sensation may last up to 1-2 days.

No adverse effects on hearing have occurred when ear protection has been properly worn.

No effects on cognitive function has been reported.

Clinical studies have reported no deaths in rTMS therapy. (Nurmikko et al.)