New publication compares NBS with fMRI for preoperative mapping in rolandic tumor surgery

HELSINKI, Finland – Aug. 15, 2012 -- Clinicians from the Departments of Neurosurgery at Katharinen hospital, Stuttgart and the University of Ulm, Günzburg, Germany have published a paper entitled Comparison of navigated transcranial magnetic stimulation and functional magnetic resonance imaging for preoperative mapping in rolandic tumor surgery.

In the paper, the Coburger et. al. describe the clinical use of the NBS System in 30 consecutive patients with tumors in the rolandic area. The NBS mapping results were compared to the results from fMRI imaging and results from both techniques were correlated with the results of intraoperative DCS. NBS mapping was found to be feasible in all patients, while fMRI was possible in only 23 of the 30 patients.

Verification of NBS-derived central sulcus localization with DCS localization was achieved in all cases, whereas, in one case, fMRI localization of the hand area proved to be postcentral when compared with DCS findings. In the study the mean accuracy to localize the motor cortex with NBS was found to be higher than with fMRI and in their conclusion, the authors state that "nTMS represents a highly valuable tool for preoperative functional planning in the clinical routine. It can complement or eventually replace fMRI for preoperative motor cortex mapping."