The NBT System is not cleared by the FDA for commercial use in Stroke Rehabilitation in the USA, for investigational use only.

Offering hope for stroke survivors

The Navigated Brain Therapy (NBT®) System is a device that uses navigated transcranial magnetic stimulation (nTMS) for use in stroke rehabilitation. Navigation is achieved by visualizing the electric field (e-field) generated by the TMS coil in a 3D image rendered from the patient’s MRI scan.

The NBT® System is a New Therapeutic Device

Stimulation intensity is calculated from the accurate measurement of brain excitability and the personal resting motor threshold (MT) of each patient. The proven accuracy confirms optimal treatment location for the individual patient, and ensures that stimulation treatment is always repeated at the same location, every time and for every session.

NBT® is currently being tested in a multicenter double-blinded, randomized, and sham-controlled trial. This new stroke therapy combines occupational therapy with nTMS.

Called the E-FIT trial (Electric Field Navigated 1Hz rTMS for Post-Stroke Motor Recovery Trial), this study is being conducted at five of the top rehabilitation sites in the United States.The study has completed patient enrollment.

It’s just immeasurable the progress that I have made!

Dwayne Nelson, Stroke Trial Patient

If you actually stimulate the surface or cortex of the brain, you can actually modulate its ability to rewire itself. Fortunately, Nexstim has made a navigated brain stimulator.

Lynn M. Rogers, PhD Lynn M. Rogers, PhD, Director, Neuralplasticity Laboratory, Rehabilitation Institute of Chicago (now Shirley Ryan Abilitylab), Illinois, USA

Indications for use and patient safety

Nexstim Navigated Brain Therapy (NBT) System 2 is not approved by the Food and Drug Administration for commercial use in Stroke Rehabilitation in the United States, for this application NBT System 2 is available to select physician for investigational use only.

CE mark Intended use

Nexstim Navigated Brain Therapy System is intended to be used for localization and assessment of the primary motor cortex for pre-procedural planning purposes. In adult patients with stroke, Nexstim NBT System is intended to provide navigated noninvasive repetitive TMS stimulation as an adjunct therapy for motor rehabilitation.

CE mark Indications for use

Nexstim MRI-Guided and E-Field Navigated Brain Therapy System (Nexstim NBT® System) is indicated for noninvasive mapping of the primary motor cortex of the brain to its cortical gyrus. Nexstim NBT® System provides information for the assessment of the primary motor cortex for pre-procedural planning. Nexstim NBT® System is indicated for MRI-guided and electric field (or E-field) navigated, noninvasive, repetitive TMS stimulation (rTMS) of the motor cortex as an adjunct therapy to rehabilitation of upper extremity motor function. Nexstim NBT® System is intended to be used by trained clinical professionals for adult patients with chronic stroke.